Publications

  1. Donati, G, Rognoni, E, Hiratsuka, T, Liakath-Ali, K, Hoste, E, Kar, G et al.. Wounding induces dedifferentiation of epidermal Gata6(+) cells and acquisition of stem cell properties. Nat. Cell Biol. 2017;19 (6):603-613. doi: 10.1038/ncb3532. PubMed PMID:28504705 .
  2. van Buggenum, JA, Gerlach, JP, Eising, S, Schoonen, L, van Eijl, RA, Tanis, SE et al.. A covalent and cleavable antibody-DNA conjugation strategy for sensitive protein detection via immuno-PCR. Sci Rep. 2016;6 :22675. doi: 10.1038/srep22675. PubMed PMID:26947912 PubMed Central PMC4780193.
  3. Stout, GJ, Stigter, EC, Essers, PB, Mulder, KW, Kolkman, A, Snijders, DS et al.. Insulin/IGF-1-mediated longevity is marked by reduced protein metabolism. Mol. Syst. Biol. 2013;9 :679. doi: 10.1038/msb.2013.35. PubMed PMID:23820781 PubMed Central PMC3734508.
  4. Wang, X, Castro, MA, Mulder, KW, Markowetz, F. Posterior association networks and functional modules inferred from rich phenotypes of gene perturbations. PLoS Comput. Biol. 2012;8 (6):e1002566. doi: 10.1371/journal.pcbi.1002566. PubMed PMID:22761558 PubMed Central PMC3386165.
  5. Mulder, KW, Wang, X, Escriu, C, Ito, Y, Schwarz, RF, Gillis, J et al.. Diverse epigenetic strategies interact to control epidermal differentiation. Nat. Cell Biol. 2012;14 (7):753-63. doi: 10.1038/ncb2520. PubMed PMID:22729083 .
  6. Goldie, SJ, Mulder, KW, Tan, DW, Lyons, SK, Sims, AH, Watt, FM et al.. FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis. Cancer Res. 2012;72 (13):3424-36. doi: 10.1158/0008-5472.CAN-12-0423. PubMed PMID:22564525 PubMed Central PMC3428932.
  7. Markowetz, F, Mulder, KW, Airoldi, EM, Lemischka, IR, Troyanskaya, OG. Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells. PLoS Comput. Biol. 2010;6 (12):e1001034. doi: 10.1371/journal.pcbi.1001034. PubMed PMID:21187909 PubMed Central PMC3002996.
  8. Lau, NC, Mulder, KW, Brenkman, AB, Mohammed, S, van den Broek, NJ, Heck, AJ et al.. Phosphorylation of Not4p functions parallel to BUR2 to regulate resistance to cellular stresses in Saccharomyces cerevisiae. PLoS ONE. 2010;5 (4):e9864. doi: 10.1371/journal.pone.0009864. PubMed PMID:20386698 PubMed Central PMC2851644.
  9. Driskell, RR, Giangreco, A, Jensen, KB, Mulder, KW, Watt, FM. Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development. 2009;136 (16):2815-23. doi: 10.1242/dev.038620. PubMed PMID:19605494 PubMed Central PMC2730408.
  10. Lau, NC, Kolkman, A, van Schaik, FM, Mulder, KW, Pijnappel, WW, Heck, AJ et al.. Human Ccr4-Not complexes contain variable deadenylase subunits. Biochem. J. 2009;422 (3):443-53. doi: 10.1042/BJ20090500. PubMed PMID:19558367 .
  11. Vermeulen, M, Mulder, KW, Denissov, S, Pijnappel, WW, van Schaik, FM, Varier, RA et al.. Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4. Cell. 2007;131 (1):58-69. doi: 10.1016/j.cell.2007.08.016. PubMed PMID:17884155 .
  12. Mulder, KW, Inagaki, A, Cameroni, E, Mousson, F, Winkler, GS, De Virgilio, C et al.. Modulation of Ubc4p/Ubc5p-mediated stress responses by the RING-finger-dependent ubiquitin-protein ligase Not4p in Saccharomyces cerevisiae. Genetics. 2007;176 (1):181-92. doi: 10.1534/genetics.106.060640. PubMed PMID:17513889 PubMed Central PMC1893070.
  13. Mulder, KW, Brenkman, AB, Inagaki, A, van den Broek, NJ, Timmers, HT. Regulation of histone H3K4 tri-methylation and PAF complex recruitment by the Ccr4-Not complex. Nucleic Acids Res. 2007;35 (7):2428-39. doi: 10.1093/nar/gkm175. PubMed PMID:17392337 PubMed Central PMC1874646.
  14. Winkler, GS, Mulder, KW, Bardwell, VJ, Kalkhoven, E, Timmers, HT. Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription. EMBO J. 2006;25 (13):3089-99. doi: 10.1038/sj.emboj.7601194. PubMed PMID:16778766 PubMed Central PMC1500986.
  15. Dreijerink, KM, Mulder, KW, Winkler, GS, Höppener, JW, Lips, CJ, Timmers, HT et al.. Menin links estrogen receptor activation to histone H3K4 trimethylation. Cancer Res. 2006;66 (9):4929-35. doi: 10.1158/0008-5472.CAN-05-4461. PubMed PMID:16651450 .
  16. Mulder, KW, Winkler, GS, Timmers, HT. DNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex. Nucleic Acids Res. 2005;33 (19):6384-92. doi: 10.1093/nar/gki938. PubMed PMID:16275785 PubMed Central PMC1278945.
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