Publications

  1. van Arensbergen, J, Pagie, L, FitzPatrick, VD, de Haas, M, Baltissen, MP, Comoglio, F et al.. High-throughput identification of human SNPs affecting regulatory element activity. Nat. Genet. 2019;51 (7):1160-1169. doi: 10.1038/s41588-019-0455-2. PubMed PMID:31253979 PubMed Central PMC6609452.
  2. van Mierlo, G, Veenstra, GJC, Vermeulen, M, Marks, H. The Complexity of PRC2 Subcomplexes. Trends Cell Biol. 2019;29 (8):660-671. doi: 10.1016/j.tcb.2019.05.004. PubMed PMID:31178244 .
  3. Hoek, TA, Khuperkar, D, Lindeboom, RGH, Sonneveld, S, Verhagen, BMP, Boersma, S et al.. Single-Molecule Imaging Uncovers Rules Governing Nonsense-Mediated mRNA Decay. Mol. Cell. 2019; :. doi: 10.1016/j.molcel.2019.05.008. PubMed PMID:31155380 .
  4. Artegiani, B, van Voorthuijsen, L, Lindeboom, RGH, Seinstra, D, Heo, I, Tapia, P et al.. Probing the Tumor Suppressor Function of BAP1 in CRISPR-Engineered Human Liver Organoids. Cell Stem Cell. 2019;24 (6):927-943.e6. doi: 10.1016/j.stem.2019.04.017. PubMed PMID:31130514 .
  5. Ignatova, VV, Jansen, PWTC, Baltissen, MP, Vermeulen, M, Schneider, R. The interactome of a family of potential methyltransferases in HeLa cells. Sci Rep. 2019;9 (1):6584. doi: 10.1038/s41598-019-43010-2. PubMed PMID:31036863 PubMed Central PMC6488577.
  6. Burgold, T, Barber, M, Kloet, S, Cramard, J, Gharbi, S, Floyd, R et al.. The Nucleosome Remodelling and Deacetylation complex suppresses transcriptional noise during lineage commitment. EMBO J. 2019;38 (12):. doi: 10.15252/embj.2018100788. PubMed PMID:31036553 PubMed Central PMC6576150.
  7. Tracey, LJ, Brooke-Bisschop, T, Jansen, PWTC, Campos, EI, Vermeulen, M, Justice, MJ et al.. The Pluripotency Regulator PRDM14 Requires Hematopoietic Regulator CBFA2T3 to Initiate Leukemia in Mice. Mol. Cancer Res. 2019;17 (7):1468-1479. doi: 10.1158/1541-7786.MCR-18-1327. PubMed PMID:31015254 PubMed Central PMC6610658.
  8. Del Gaudio, N, Di Costanzo, A, Liu, NQ, Conte, L, Migliaccio, A, Vermeulen, M et al.. BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition. Cell Death Dis. 2019;10 (5):338. doi: 10.1038/s41419-019-1570-9. PubMed PMID:31000698 PubMed Central PMC6472371.
  9. Furlan, C, Dirks, RAM, Thomas, PC, Jones, RC, Wang, J, Lynch, M et al.. Miniaturised interaction proteomics on a microfluidic platform with ultra-low input requirements. Nat Commun. 2019;10 (1):1525. doi: 10.1038/s41467-019-09533-y. PubMed PMID:30948724 PubMed Central PMC6449397.
  10. Wassef, M, Luscan, A, Aflaki, S, Zielinski, D, Jansen, PWTC, Baymaz, HI et al.. EZH1/2 function mostly within canonical PRC2 and exhibit proliferation-dependent redundancy that shapes mutational signatures in cancer. Proc. Natl. Acad. Sci. U.S.A. 2019;116 (13):6075-6080. doi: 10.1073/pnas.1814634116. PubMed PMID:30867289 PubMed Central PMC6442582.
  11. Yi, G, Mandoli, A, Jussen, L, Tijchon, E, van Bergen, MGJM, Cordonnier, G et al.. CBFβ-MYH11 interferes with megakaryocyte differentiation via modulating a gene program that includes GATA2 and KLF1. Blood Cancer J. 2019;9 (3):33. doi: 10.1038/s41408-019-0194-8. PubMed PMID:30850577 PubMed Central PMC6408575.
  12. van Oorschot, R, Hansen, M, Koornneef, JM, Marneth, AE, Bergevoet, SM, van Bergen, MGJM et al.. Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets. Haematologica. 2019;104 (7):1460-1472. doi: 10.3324/haematol.2018.194555. PubMed PMID:30655368 PubMed Central PMC6601108.
  13. Joosten, J, Miesen, P, Taşköprü, E, Pennings, B, Jansen, PWTC, Huynen, MA et al.. The Tudor protein Veneno assembles the ping-pong amplification complex that produces viral piRNAs in Aedes mosquitoes. Nucleic Acids Res. 2019;47 (5):2546-2559. doi: 10.1093/nar/gky1266. PubMed PMID:30566680 PubMed Central PMC6411831.
  14. van Mierlo, G, Dirks, RAM, De Clerck, L, Brinkman, AB, Huth, M, Kloet, SL et al.. Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency. Cell Stem Cell. 2019;24 (1):123-137.e8. doi: 10.1016/j.stem.2018.10.017. PubMed PMID:30472157 .
  15. Brien, GL, Remillard, D, Shi, J, Hemming, ML, Chabon, J, Wynne, K et al.. Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma. Elife. 2018;7 :. doi: 10.7554/eLife.41305. PubMed PMID:30431433 PubMed Central PMC6277197.
  16. Palmer, WH, Joosten, J, Overheul, GJ, Jansen, PW, Vermeulen, M, Obbard, DJ et al.. Induction and Suppression of NF-κB Signalling by a DNA Virus of Drosophila. J. Virol. 2019;93 (3):. doi: 10.1128/JVI.01443-18. PubMed PMID:30404807 PubMed Central PMC6340046.
  17. Kloet, SL, Karemaker, ID, van Voorthuijsen, L, Lindeboom, RGH, Baltissen, MP, Edupuganti, RR et al.. NuRD-interacting protein ZFP296 regulates genome-wide NuRD localization and differentiation of mouse embryonic stem cells. Nat Commun. 2018;9 (1):4588. doi: 10.1038/s41467-018-07063-7. PubMed PMID:30389936 PubMed Central PMC6214896.
  18. Tanis, SEJ, Jansen, PWTC, Zhou, H, van Heeringen, SJ, Vermeulen, M, Kretz, M et al.. Splicing and Chromatin Factors Jointly Regulate Epidermal Differentiation. Cell Rep. 2018;25 (5):1292-1303.e5. doi: 10.1016/j.celrep.2018.10.017. PubMed PMID:30380419 .
  19. Lindeboom, RGH, Smits, AH, Perino, M, Veenstra, GJC, Vermeulen, M. Mass Spectrometry-Based Absolute Quantification of Single Xenopus Embryo Proteomes. Cold Spring Harb Protoc. 2019;2019 (6):pdb.prot098376. doi: 10.1101/pdb.prot098376. PubMed PMID:30104410 .
  20. Kole, K, Lindeboom, RGH, Baltissen, MPA, Jansen, PWTC, Vermeulen, M, Tiesinga, P et al.. Erratum to: Proteomic landscape of the primary somatosensory cortex upon sensory deprivation. Gigascience. 2018;7 (7):. doi: 10.1093/gigascience/giy041. PubMed PMID:30053288 PubMed Central PMC6055539.
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