Publications

  1. Søndergaard, JN, van Heeringen, SJ, Looman, MWG, Tang, C, Triantis, V, Louche, P et al.. Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4. Front Immunol. 2018;9 :1420. doi: 10.3389/fimmu.2018.01420. PubMed PMID:29988341 PubMed Central PMC6023963.
  2. Singh, AA, Petraglia, F, Nebbioso, A, Yi, G, Conte, M, Valente, S et al.. Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia. Oncotarget. 2018;9 (39):25647-25660. doi: 10.18632/oncotarget.25429. PubMed PMID:29876014 PubMed Central PMC5986653.
  3. Petraglia, F, Singh, AA, Carafa, V, Nebbioso, A, Conte, M, Scisciola, L et al.. Combined HAT/EZH2 modulation leads to cancer-selective cell death. Oncotarget. 2018;9 (39):25630-25646. doi: 10.18632/oncotarget.25428. PubMed PMID:29876013 PubMed Central PMC5986654.
  4. Beekman, R, Chapaprieta, V, Russiñol, N, Vilarrasa-Blasi, R, Verdaguer-Dot, N, Martens, JHA et al.. The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia. Nat. Med. 2018;24 (6):868-880. doi: 10.1038/s41591-018-0028-4. PubMed PMID:29785028 .
  5. Dell'Aversana, C, Giorgio, C, D'Amato, L, Lania, G, Matarese, F, Saeed, S et al.. miR-194-5p/BCLAF1 deregulation in AML tumorigenesis. Leukemia. 2018;32 (2):573. doi: 10.1038/leu.2017.310. PubMed PMID:29271969 .
  6. Glodzik, D, Morganella, S, Davies, H, Simpson, PT, Li, Y, Zou, X et al.. Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nat. Genet. 2017;49 (11):1661. doi: 10.1038/ng1117-1661a. PubMed PMID:29074948 .
  7. Nebbioso, A, Benedetti, R, Conte, M, Carafa, V, De Bellis, F, Shaik, J et al.. Time-resolved analysis of DNA-protein interactions in living cells by UV laser pulses. Sci Rep. 2017;7 (1):11725. doi: 10.1038/s41598-017-12010-5. PubMed PMID:28916762 PubMed Central PMC5601431.
  8. Marneth, AE, Prange, KHM, Al Hinai, ASA, Bergevoet, SM, Tesi, N, Janssen-Megens, EM et al.. C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation. Leukemia. 2018;32 (3):828-836. doi: 10.1038/leu.2017.280. PubMed PMID:28871137 .
  9. Petersen, R, Lambourne, JJ, Javierre, BM, Grassi, L, Kreuzhuber, R, Ruklisa, D et al.. Platelet function is modified by common sequence variation in megakaryocyte super enhancers. Nat Commun. 2017;8 :16058. doi: 10.1038/ncomms16058. PubMed PMID:28703137 PubMed Central PMC5511350.
  10. Ju, YS, Martincorena, I, Gerstung, M, Petljak, M, Alexandrov, LB, Rahbari, R et al.. Somatic mutations reveal asymmetric cellular dynamics in the early human embryo. Nature. 2017;543 (7647):714-718. doi: 10.1038/nature21703. PubMed PMID:28329761 .
  11. Davies, H, Glodzik, D, Morganella, S, Yates, LR, Staaf, J, Zou, X et al.. HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures. Nat. Med. 2017;23 (4):517-525. doi: 10.1038/nm.4292. PubMed PMID:28288110 PubMed Central PMC5833945.
  12. Dell'Aversana, C, Giorgio, C, D'Amato, L, Lania, G, Matarese, F, Saeed, S et al.. miR-194-5p/BCLAF1 deregulation in AML tumorigenesis. Leukemia. 2017;31 (11):2315-2325. doi: 10.1038/leu.2017.64. PubMed PMID:28216661 PubMed Central PMC5668498.
  13. Prange, KHM, Mandoli, A, Kuznetsova, T, Wang, SY, Sotoca, AM, Marneth, AE et al.. MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia. Oncogene. 2017;36 (23):3346-3356. doi: 10.1038/onc.2016.488. PubMed PMID:28114278 PubMed Central PMC5474565.
  14. Glodzik, D, Morganella, S, Davies, H, Simpson, PT, Li, Y, Zou, X et al.. A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nat. Genet. 2017;49 (3):341-348. doi: 10.1038/ng.3771. PubMed PMID:28112740 PubMed Central PMC5988034.
  15. Astle, WJ, Elding, H, Jiang, T, Allen, D, Ruklisa, D, Mann, AL et al.. The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Cell. 2016;167 (5):1415-1429.e19. doi: 10.1016/j.cell.2016.10.042. PubMed PMID:27863252 PubMed Central PMC5300907.
  16. Chen, L, Ge, B, Casale, FP, Vasquez, L, Kwan, T, Garrido-Martín, D et al.. Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. Cell. 2016;167 (5):1398-1414.e24. doi: 10.1016/j.cell.2016.10.026. PubMed PMID:27863251 PubMed Central PMC5119954.
  17. Novakovic, B, Habibi, E, Wang, SY, Arts, RJW, Davar, R, Megchelenbrink, W et al.. β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance. Cell. 2016;167 (5):1354-1368.e14. doi: 10.1016/j.cell.2016.09.034. PubMed PMID:27863248 PubMed Central PMC5927328.
  18. Breeze, CE, Paul, DS, van Dongen, J, Butcher, LM, Ambrose, JC, Barrett, JE et al.. eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data. Cell Rep. 2016;17 (8):2137-2150. doi: 10.1016/j.celrep.2016.10.059. PubMed PMID:27851974 PubMed Central PMC5120369.
  19. Schuyler, RP, Merkel, A, Raineri, E, Altucci, L, Vellenga, E, Martens, JHA et al.. Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems. Cell Rep. 2016;17 (8):2101-2111. doi: 10.1016/j.celrep.2016.10.054. PubMed PMID:27851971 PubMed Central PMC5889099.
  20. Mandoli, A, Singh, AA, Prange, KHM, Tijchon, E, Oerlemans, M, Dirks, R et al.. The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs. Cell Rep. 2016;17 (8):2087-2100. doi: 10.1016/j.celrep.2016.08.082. PubMed PMID:27851970 .
Search PubMed