Publications

  1. Poziello, A, Nebbioso, A, Stunnenberg, HG, Martens, JHA, Carafa, V, Altucci, L et al.. Recent insights into Histone Acetyltransferase-1: biological function and involvement in pathogenesis. Epigenetics. 2020; :1-13. doi: 10.1080/15592294.2020.1827723. PubMed PMID:33016232 .
  2. Ordoñez, R, Kulis, M, Russiñol, N, Chapaprieta, V, Carrasco-Leon, A, García-Torre, B et al.. Chromatin activation as a unifying principle underlying pathogenic mechanisms in multiple myeloma. Genome Res. 2020;30 (9):1217-1227. doi: 10.1101/gr.265520.120. PubMed PMID:32820006 PubMed Central PMC7545147.
  3. Grassi, L, Izuogu, OG, Jorge, NAN, Seyres, D, Bustamante, M, Burden, F et al.. Cell type specific novel lncRNAs and circRNAs in the BLUEPRINT haematopoietic transcriptomes atlas. Haematologica. 2020; :. doi: 10.3324/haematol.2019.238147. PubMed PMID:32703790 .
  4. Cieslak, A, Charbonnier, G, Tesio, M, Mathieu, EL, Belhocine, M, Touzart, A et al.. Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation. J Exp Med. 2020;217 (9):. doi: 10.1084/jem.20192360. PubMed PMID:32667968 PubMed Central PMC7478722.
  5. Del Gaudio, N, Di Costanzo, A, Liu, NQ, Conte, L, Migliaccio, A, Vermeulen, M et al.. BRD9 binds cell type-specific chromatin regions regulating leukemic cell survival via STAT5 inhibition. Cell Death Dis. 2019;10 (5):338. doi: 10.1038/s41419-019-1570-9. PubMed PMID:31000698 PubMed Central PMC6472371.
  6. Brinkman, AB, Nik-Zainal, S, Simmer, F, Rodríguez-González, FG, Smid, M, Alexandrov, LB et al.. Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation. Nat Commun. 2019;10 (1):1749. doi: 10.1038/s41467-019-09828-0. PubMed PMID:30988298 PubMed Central PMC6465362.
  7. Smid, M, Wilting, SM, Uhr, K, Rodríguez-González, FG, de Weerd, V, Prager-Van der Smissen, WJC et al.. The circular RNome of primary breast cancer. Genome Res. 2019;29 (3):356-366. doi: 10.1101/gr.238121.118. PubMed PMID:30692147 PubMed Central PMC6396421.
  8. Yi, G, Wierenga, ATJ, Petraglia, F, Narang, P, Janssen-Megens, EM, Mandoli, A et al.. Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes. Cell Rep. 2019;26 (4):1059-1069.e6. doi: 10.1016/j.celrep.2018.12.098. PubMed PMID:30673601 PubMed Central PMC6363099.
  9. Nik-Zainal, S, Davies, H, Staaf, J, Ramakrishna, M, Glodzik, D, Zou, X et al.. Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences. Nature. 2019;566 (7742):E1. doi: 10.1038/s41586-019-0883-2. PubMed PMID:30659290 .
  10. Teo, K, Gómez-Cuadrado, L, Tenhagen, M, Byron, A, Rätze, M, van Amersfoort, M et al.. E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer. Sci Rep. 2018;8 (1):15454. doi: 10.1038/s41598-018-33525-5. PubMed PMID:30337563 PubMed Central PMC6193986.
  11. Grassi, L, Pourfarzad, F, Ullrich, S, Merkel, A, Were, F, Carrillo-de-Santa-Pau, E et al.. Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils. Cell Rep. 2018;24 (10):2784-2794. doi: 10.1016/j.celrep.2018.08.018. PubMed PMID:30184510 PubMed Central PMC6326331.
  12. Søndergaard, JN, van Heeringen, SJ, Looman, MWG, Tang, C, Triantis, V, Louche, P et al.. Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4. Front Immunol. 2018;9 :1420. doi: 10.3389/fimmu.2018.01420. PubMed PMID:29988341 PubMed Central PMC6023963.
  13. Singh, AA, Petraglia, F, Nebbioso, A, Yi, G, Conte, M, Valente, S et al.. Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia. Oncotarget. 2018;9 (39):25647-25660. doi: 10.18632/oncotarget.25429. PubMed PMID:29876014 PubMed Central PMC5986653.
  14. Petraglia, F, Singh, AA, Carafa, V, Nebbioso, A, Conte, M, Scisciola, L et al.. Combined HAT/EZH2 modulation leads to cancer-selective cell death. Oncotarget. 2018;9 (39):25630-25646. doi: 10.18632/oncotarget.25428. PubMed PMID:29876013 PubMed Central PMC5986654.
  15. Beekman, R, Chapaprieta, V, Russiñol, N, Vilarrasa-Blasi, R, Verdaguer-Dot, N, Martens, JHA et al.. The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia. Nat Med. 2018;24 (6):868-880. doi: 10.1038/s41591-018-0028-4. PubMed PMID:29785028 PubMed Central PMC6363101.
  16. Dell'Aversana, C, Giorgio, C, D'Amato, L, Lania, G, Matarese, F, Saeed, S et al.. miR-194-5p/BCLAF1 deregulation in AML tumorigenesis. Leukemia. 2018;32 (2):573. doi: 10.1038/leu.2017.310. PubMed PMID:29271969 PubMed Central PMC7608254.
  17. Glodzik, D, Morganella, S, Davies, H, Simpson, PT, Li, Y, Zou, X et al.. Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nat Genet. 2017;49 (11):1661. doi: 10.1038/ng1117-1661a. PubMed PMID:29074948 .
  18. Nebbioso, A, Benedetti, R, Conte, M, Carafa, V, De Bellis, F, Shaik, J et al.. Time-resolved analysis of DNA-protein interactions in living cells by UV laser pulses. Sci Rep. 2017;7 (1):11725. doi: 10.1038/s41598-017-12010-5. PubMed PMID:28916762 PubMed Central PMC5601431.
  19. Marneth, AE, Prange, KHM, Al Hinai, ASA, Bergevoet, SM, Tesi, N, Janssen-Megens, EM et al.. C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation. Leukemia. 2018;32 (3):828-836. doi: 10.1038/leu.2017.280. PubMed PMID:28871137 .
  20. Petersen, R, Lambourne, JJ, Javierre, BM, Grassi, L, Kreuzhuber, R, Ruklisa, D et al.. Platelet function is modified by common sequence variation in megakaryocyte super enhancers. Nat Commun. 2017;8 :16058. doi: 10.1038/ncomms16058. PubMed PMID:28703137 PubMed Central PMC5511350.
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