Publications

  1. Wang, C, Nanni, L, Novakovic, B, Megchelenbrink, W, Kuznetsova, T, Stunnenberg, HG et al.. Extensive epigenomic integration of the glucocorticoid response in primary human monocytes and in vitro derived macrophages. Sci Rep. 2019;9 (1):2772. doi: 10.1038/s41598-019-39395-9. PubMed PMID:30809020 PubMed Central PMC6391480.
  2. Gerlach, JP, van Buggenum, JAG, Tanis, SEJ, Hogeweg, M, Heuts, BMH, Muraro, MJ et al.. Combined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells. Sci Rep. 2019;9 (1):1469. doi: 10.1038/s41598-018-37977-7. PubMed PMID:30728416 PubMed Central PMC6365588.
  3. Smid, M, Wilting, SM, Uhr, K, Rodríguez-González, FG, de Weerd, V, Prager-Van der Smissen, WJC et al.. The circular RNome of primary breast cancer. Genome Res. 2019;29 (3):356-366. doi: 10.1101/gr.238121.118. PubMed PMID:30692147 .
  4. Yi, G, Wierenga, ATJ, Petraglia, F, Narang, P, Janssen-Megens, EM, Mandoli, A et al.. Chromatin-Based Classification of Genetically Heterogeneous AMLs into Two Distinct Subtypes with Diverse Stemness Phenotypes. Cell Rep. 2019;26 (4):1059-1069.e6. doi: 10.1016/j.celrep.2018.12.098. PubMed PMID:30673601 PubMed Central PMC6363099.
  5. Nik-Zainal, S, Davies, H, Staaf, J, Ramakrishna, M, Glodzik, D, Zou, X et al.. Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences. Nature. 2019;566 (7742):E1. doi: 10.1038/s41586-019-0883-2. PubMed PMID:30659290 .
  6. Qu, J, Tanis, SEJ, Smits, JPH, Kouwenhoven, EN, Oti, M, van den Bogaard, EH et al.. Mutant p63 Affects Epidermal Cell Identity through Rewiring the Enhancer Landscape. Cell Rep. 2018;25 (12):3490-3503.e4. doi: 10.1016/j.celrep.2018.11.039. PubMed PMID:30566872 .
  7. Teo, K, Gómez-Cuadrado, L, Tenhagen, M, Byron, A, Rätze, M, van Amersfoort, M et al.. E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer. Sci Rep. 2018;8 (1):15454. doi: 10.1038/s41598-018-33525-5. PubMed PMID:30337563 PubMed Central PMC6193986.
  8. Grassi, L, Pourfarzad, F, Ullrich, S, Merkel, A, Were, F, Carrillo-de-Santa-Pau, E et al.. Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils. Cell Rep. 2018;24 (10):2784-2794. doi: 10.1016/j.celrep.2018.08.018. PubMed PMID:30184510 PubMed Central PMC6326331.
  9. Hornig, NC, Rodens, P, Dörr, H, Hubner, NC, Kulle, AE, Schweikert, HU et al.. Epigenetic Repression of Androgen Receptor Transcription in Mutation-Negative Androgen Insensitivity Syndrome (AIS Type II). J. Clin. Endocrinol. Metab. 2018;103 (12):4617-4627. doi: 10.1210/jc.2018-00052. PubMed PMID:30124873 .
  10. Richter, L, Landsverk, OJB, Atlasy, N, Bujko, A, Yaqub, S, Horneland, R et al.. Transcriptional profiling reveals monocyte-related macrophages phenotypically resembling DC in human intestine. Mucosal Immunol. 2018;11 (5):1512-1523. doi: 10.1038/s41385-018-0060-1. PubMed PMID:30038215 .
  11. Bernardo, AS, Jouneau, A, Marks, H, Kensche, P, Kobolak, J, Freude, K et al.. Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state. Biol Open. 2018;7 (8):. doi: 10.1242/bio.033282. PubMed PMID:30026265 PubMed Central PMC6124576.
  12. Søndergaard, JN, van Heeringen, SJ, Looman, MWG, Tang, C, Triantis, V, Louche, P et al.. Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4. Front Immunol. 2018;9 :1420. doi: 10.3389/fimmu.2018.01420. PubMed PMID:29988341 PubMed Central PMC6023963.
  13. van Buggenum, JAG, Gerlach, JP, Tanis, SEJ, Hogeweg, M, Jansen, PWTC, Middelwijk, J et al.. Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells. Nat Commun. 2018;9 (1):2384. doi: 10.1038/s41467-018-04761-0. PubMed PMID:29921844 PubMed Central PMC6008431.
  14. Singh, AA, Petraglia, F, Nebbioso, A, Yi, G, Conte, M, Valente, S et al.. Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia. Oncotarget. 2018;9 (39):25647-25660. doi: 10.18632/oncotarget.25429. PubMed PMID:29876014 PubMed Central PMC5986653.
  15. Petraglia, F, Singh, AA, Carafa, V, Nebbioso, A, Conte, M, Scisciola, L et al.. Combined HAT/EZH2 modulation leads to cancer-selective cell death. Oncotarget. 2018;9 (39):25630-25646. doi: 10.18632/oncotarget.25428. PubMed PMID:29876013 PubMed Central PMC5986654.
  16. Beekman, R, Chapaprieta, V, Russiñol, N, Vilarrasa-Blasi, R, Verdaguer-Dot, N, Martens, JHA et al.. The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia. Nat. Med. 2018;24 (6):868-880. doi: 10.1038/s41591-018-0028-4. PubMed PMID:29785028 PubMed Central PMC6363101.
  17. Atlasi, Y, Stunnenberg, HG. Brd4-independence in ground state pluripotency. Nat. Cell Biol. 2018;20 (5):513-515. doi: 10.1038/s41556-018-0099-y. PubMed PMID:29662177 .
  18. Dubos, A, Meziane, H, Iacono, G, Curie, A, Riet, F, Martin, C et al.. A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations. Hum. Mol. Genet. 2018;27 (12):2138-2153. doi: 10.1093/hmg/ddy122. PubMed PMID:29659809 PubMed Central PMC5985730.
  19. Iacono, G, Dubos, A, Méziane, H, Benevento, M, Habibi, E, Mandoli, A et al.. Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome. Nucleic Acids Res. 2018;46 (10):4950-4965. doi: 10.1093/nar/gky196. PubMed PMID:29554304 PubMed Central PMC6007260.
  20. Carafa, V, Nebbioso, A, Cuomo, F, Rotili, D, Cobellis, G, Bontempo, P et al.. RIP1-HAT1-SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer. Clin. Cancer Res. 2018;24 (12):2886-2900. doi: 10.1158/1078-0432.CCR-17-3081. PubMed PMID:29535128 .
Search PubMed