Publications

  1. Nebbioso, A, Benedetti, R, Conte, M, Carafa, V, De Bellis, F, Shaik, J et al.. Time-resolved analysis of DNA-protein interactions in living cells by UV laser pulses. Sci Rep. 2017;7 (1):11725. doi: 10.1038/s41598-017-12010-5. PubMed PMID:28916762 .
  2. Marneth, AE, Prange, KHM, Al Hinai, ASA, Bergevoet, SM, Tesi, N, Janssen-Megens, E et al.. C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation. Leukemia. 2017; :. doi: 10.1038/leu.2017.280. PubMed PMID:28871137 .
  3. Edupuganti, RR, Geiger, S, Lindeboom, RGH, Shi, H, Hsu, PJ, Lu, Z et al.. N(6)-methyladenosine (m(6)A) recruits and repels proteins to regulate mRNA homeostasis. Nat. Struct. Mol. Biol. 2017; :. doi: 10.1038/nsmb.3462. PubMed PMID:28869609 .
  4. Liu, Y, Reynolds, LM, Ding, J, Hou, L, Lohman, K, Young, T et al.. Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis. Nat Commun. 2017;8 (1):393. doi: 10.1038/s41467-017-00517-4. PubMed PMID:28855511 PubMed Central PMC5577184.
  5. Atlasi, Y, Stunnenberg, HG. The interplay of epigenetic marks during stem cell differentiation and development. Nat. Rev. Genet. 2017; :. doi: 10.1038/nrg.2017.57. PubMed PMID:28804139 .
  6. Habibi, E, Stunnenberg, HG. Transcriptional and epigenetic control in mouse pluripotency: lessons from in vivo and in vitro studies. Curr. Opin. Genet. Dev. 2017;46 :114-122. doi: 10.1016/j.gde.2017.07.005. PubMed PMID:28763675 .
  7. Arbogast, T, Iacono, G, Chevalier, C, Afinowi, NO, Houbaert, X, van Eede, MC et al.. Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition. PLoS Genet. 2017;13 (7):e1006886. doi: 10.1371/journal.pgen.1006886. PubMed PMID:28704368 PubMed Central PMC5531616.
  8. Petersen, R, Lambourne, JJ, Javierre, BM, Grassi, L, Kreuzhuber, R, Ruklisa, D et al.. Platelet function is modified by common sequence variation in megakaryocyte super enhancers. Nat Commun. 2017;8 :16058. doi: 10.1038/ncomms16058. PubMed PMID:28703137 PubMed Central PMC5511350.
  9. Richardson, R, Mitchell, K, Hammond, NL, Mollo, MR, Kouwenhoven, EN, Wyatt, ND et al.. p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate. PLoS Genet. 2017;13 (6):e1006828. doi: 10.1371/journal.pgen.1006828. PubMed PMID:28604778 PubMed Central PMC5484519.
  10. Crişan, TO, Cleophas, MCP, Novakovic, B, Erler, K, van de Veerdonk, FL, Stunnenberg, HG et al.. Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway. Proc. Natl. Acad. Sci. U.S.A. 2017;114 (21):5485-5490. doi: 10.1073/pnas.1620910114. PubMed PMID:28484006 PubMed Central PMC5448210.
  11. Ung, DC, Iacono, G, Méziane, H, Blanchard, E, Papon, MA, Selten, M et al.. Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse. Mol. Psychiatry. 2017; :. doi: 10.1038/mp.2017.39. PubMed PMID:28416808 .
  12. Davies, H, Glodzik, D, Morganella, S, Yates, LR, Staaf, J, Zou, X et al.. HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures. Nat. Med. 2017;23 (4):517-525. doi: 10.1038/nm.4292. PubMed PMID:28288110 .
  13. Cheung, WA, Shao, X, Morin, A, Siroux, V, Kwan, T, Ge, B et al.. Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome. Genome Biol. 2017;18 (1):50. doi: 10.1186/s13059-017-1173-7. PubMed PMID:28283040 PubMed Central PMC5346261.
  14. Dell'Aversana, C, Giorgio, C, D'Amato, L, Lania, G, Matarese, F, Saeed, S et al.. miR-194-5p/BCLAF1 deregulation in AML tumorigenesis. Leukemia. 2017; :. doi: 10.1038/leu.2017.64. PubMed PMID:28216661 .
  15. Liu, NQ, Ter Huurne, M, Nguyen, LN, Peng, T, Wang, SY, Studd, JB et al.. The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression. Nat Commun. 2017;8 :14418. doi: 10.1038/ncomms14418. PubMed PMID:28195176 PubMed Central PMC5316867.
  16. Kalkan, T, Olova, N, Roode, M, Mulas, C, Lee, HJ, Nett, I et al.. Tracking the embryonic stem cell transition from ground state pluripotency. Development. 2017;144 (7):1221-1234. doi: 10.1242/dev.142711. PubMed PMID:28174249 PubMed Central PMC5399622.
  17. Ecker, S, Chen, L, Pancaldi, V, Bagger, FO, Fernández, JM, Carrillo de Santa Pau, E et al.. Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. Genome Biol. 2017;18 (1):18. doi: 10.1186/s13059-017-1156-8. PubMed PMID:28126036 PubMed Central PMC5270224.
  18. Prange, KHM, Mandoli, A, Kuznetsova, T, Wang, SY, Sotoca, AM, Marneth, AE et al.. MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia. Oncogene. 2017;36 (23):3346-3356. doi: 10.1038/onc.2016.488. PubMed PMID:28114278 PubMed Central PMC5474565.
  19. Glodzik, D, Morganella, S, Davies, H, Simpson, PT, Li, Y, Zou, X et al.. A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nat. Genet. 2017;49 (3):341-348. doi: 10.1038/ng.3771. PubMed PMID:28112740 .
  20. Tomaz, RA, Harman, JL, Karimlou, D, Weavers, L, Fritsch, L, Bou-Kheir, T et al.. Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation. Development. 2017;144 (4):567-579. doi: 10.1242/dev.142489. PubMed PMID:28087629 PubMed Central PMC5312034.
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