Publications

  1. Søndergaard, JN, van Heeringen, SJ, Looman, MWG, Tang, C, Triantis, V, Louche, P et al.. Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4. Front Immunol. 2018;9 :1420. doi: 10.3389/fimmu.2018.01420. PubMed PMID:29988341 PubMed Central PMC6023963.
  2. van Buggenum, JAG, Gerlach, JP, Tanis, SEJ, Hogeweg, M, Jansen, PWTC, Middelwijk, J et al.. Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells. Nat Commun. 2018;9 (1):2384. doi: 10.1038/s41467-018-04761-0. PubMed PMID:29921844 PubMed Central PMC6008431.
  3. Singh, AA, Petraglia, F, Nebbioso, A, Yi, G, Conte, M, Valente, S et al.. Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia. Oncotarget. 2018;9 (39):25647-25660. doi: 10.18632/oncotarget.25429. PubMed PMID:29876014 PubMed Central PMC5986653.
  4. Petraglia, F, Singh, AA, Carafa, V, Nebbioso, A, Conte, M, Scisciola, L et al.. Combined HAT/EZH2 modulation leads to cancer-selective cell death. Oncotarget. 2018;9 (39):25630-25646. doi: 10.18632/oncotarget.25428. PubMed PMID:29876013 PubMed Central PMC5986654.
  5. Beekman, R, Chapaprieta, V, Russiñol, N, Vilarrasa-Blasi, R, Verdaguer-Dot, N, Martens, JHA et al.. The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia. Nat. Med. 2018;24 (6):868-880. doi: 10.1038/s41591-018-0028-4. PubMed PMID:29785028 .
  6. Atlasi, Y, Stunnenberg, HG. Brd4-independence in ground state pluripotency. Nat. Cell Biol. 2018;20 (5):513-515. doi: 10.1038/s41556-018-0099-y. PubMed PMID:29662177 .
  7. Dubos, A, Meziane, H, Iacono, G, Curie, A, Riet, F, Martin, C et al.. A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations. Hum. Mol. Genet. 2018;27 (12):2138-2153. doi: 10.1093/hmg/ddy122. PubMed PMID:29659809 PubMed Central PMC5985730.
  8. Iacono, G, Dubos, A, Méziane, H, Benevento, M, Habibi, E, Mandoli, A et al.. Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome. Nucleic Acids Res. 2018;46 (10):4950-4965. doi: 10.1093/nar/gky196. PubMed PMID:29554304 PubMed Central PMC6007260.
  9. Carafa, V, Nebbioso, A, Cuomo, F, Rotili, D, Cobellis, G, Bontempo, P et al.. RIP1-HAT1-SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer. Clin. Cancer Res. 2018;24 (12):2886-2900. doi: 10.1158/1078-0432.CCR-17-3081. PubMed PMID:29535128 .
  10. Bertero, A, Brown, S, Madrigal, P, Osnato, A, Ortmann, D, Yiangou, L et al.. The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency. Nature. 2018;555 (7695):256-259. doi: 10.1038/nature25784. PubMed PMID:29489750 PubMed Central PMC5951268.
  11. Arts, RJW, Moorlag, SJCFM, Novakovic, B, Li, Y, Wang, SY, Oosting, M et al.. BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity. Cell Host Microbe. 2018;23 (1):89-100.e5. doi: 10.1016/j.chom.2017.12.010. PubMed PMID:29324233 .
  12. Iacono, G, Benevento, M, Dubos, A, Herault, Y, van Bokhoven, H, Nadif Kasri, N et al.. Integrated transcriptional analysis unveils the dynamics of cellular differentiation in the developing mouse hippocampus. Sci Rep. 2017;7 (1):18073. doi: 10.1038/s41598-017-18287-w. PubMed PMID:29273784 PubMed Central PMC5741714.
  13. Bujko, A, Atlasy, N, Landsverk, OJB, Richter, L, Yaqub, S, Horneland, R et al.. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J. Exp. Med. 2018;215 (2):441-458. doi: 10.1084/jem.20170057. PubMed PMID:29273642 PubMed Central PMC5789404.
  14. Dell'Aversana, C, Giorgio, C, D'Amato, L, Lania, G, Matarese, F, Saeed, S et al.. miR-194-5p/BCLAF1 deregulation in AML tumorigenesis. Leukemia. 2018;32 (2):573. doi: 10.1038/leu.2017.310. PubMed PMID:29271969 .
  15. Novakovic, B, Stunnenberg, HG. I Remember You: Epigenetic Priming in Epithelial Stem Cells. Immunity. 2017;47 (6):1019-1021. doi: 10.1016/j.immuni.2017.12.005. PubMed PMID:29262345 .
  16. Glodzik, D, Morganella, S, Davies, H, Simpson, PT, Li, Y, Zou, X et al.. Corrigendum: A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nat. Genet. 2017;49 (11):1661. doi: 10.1038/ng1117-1661a. PubMed PMID:29074948 .
  17. Ter Huurne, M, Chappell, J, Dalton, S, Stunnenberg, HG. Distinct Cell-Cycle Control in Two Different States of Mouse Pluripotency. Cell Stem Cell. 2017;21 (4):449-455.e4. doi: 10.1016/j.stem.2017.09.004. PubMed PMID:28985526 PubMed Central PMC5658514.
  18. Fisher, CL, Marks, H, Cho, LT, Andrews, R, Wormald, S, Carroll, T et al.. An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers. Nucleic Acids Res. 2017;45 (21):e174. doi: 10.1093/nar/gkx811. PubMed PMID:28981838 PubMed Central PMC5716182.
  19. Nebbioso, A, Benedetti, R, Conte, M, Carafa, V, De Bellis, F, Shaik, J et al.. Time-resolved analysis of DNA-protein interactions in living cells by UV laser pulses. Sci Rep. 2017;7 (1):11725. doi: 10.1038/s41598-017-12010-5. PubMed PMID:28916762 PubMed Central PMC5601431.
  20. Marneth, AE, Prange, KHM, Al Hinai, ASA, Bergevoet, SM, Tesi, N, Janssen-Megens, EM et al.. C-terminal BRE overexpression in 11q23-rearranged and t(8;16) acute myeloid leukemia is caused by intragenic transcription initiation. Leukemia. 2018;32 (3):828-836. doi: 10.1038/leu.2017.280. PubMed PMID:28871137 .
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