Publications

  1. Tomaz, RA, Harman, JL, Karimlou, D, Weavers, L, Fritsch, L, Bou-Kheir, T et al.. Jmjd2c/Kdm4c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation. Development. 2017; :. doi: 10.1242/dev.142489. PubMed PMID:28087629 .
  2. D'Aniello, C, Habibi, E, Cermola, F, Paris, D, Russo, F, Fiorenzano, A et al.. Vitamin C and l-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum. Stem Cell Reports. 2017;8 (1):1-10. doi: 10.1016/j.stemcr.2016.11.011. PubMed PMID:28017658 .
  3. Stunnenberg, HG, International Human Epigenome Consortium, Hirst, M. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. Cell. 2016;167 (7):1897. doi: 10.1016/j.cell.2016.12.002. PubMed PMID:27984737 .
  4. Dirks, RA, Stunnenberg, HG, Marks, H. Genome-wide epigenomic profiling for biomarker discovery. Clin Epigenetics. 2016;8 :122. doi: 10.1186/s13148-016-0284-4. PubMed PMID:27895806 PubMed Central PMC5117701.
  5. Farlik, M, Halbritter, F, Müller, F, Choudry, FA, Ebert, P, Klughammer, J et al.. DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation. Cell Stem Cell. 2016;19 (6):808-822. doi: 10.1016/j.stem.2016.10.019. PubMed PMID:27867036 PubMed Central PMC5145815.
  6. Arts, RJ, Novakovic, B, Ter Horst, R, Carvalho, A, Bekkering, S, Lachmandas, E et al.. Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metab. 2016;24 (6):807-819. doi: 10.1016/j.cmet.2016.10.008. PubMed PMID:27866838 .
  7. Astle, WJ, Elding, H, Jiang, T, Allen, D, Ruklisa, D, Mann, AL et al.. The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Cell. 2016;167 (5):1415-1429.e19. doi: 10.1016/j.cell.2016.10.042. PubMed PMID:27863252 .
  8. Chen, L, Ge, B, Casale, FP, Vasquez, L, Kwan, T, Garrido-Martín, D et al.. Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. Cell. 2016;167 (5):1398-1414.e24. doi: 10.1016/j.cell.2016.10.026. PubMed PMID:27863251 PubMed Central PMC5119954.
  9. Javierre, BM, Burren, OS, Wilder, SP, Kreuzhuber, R, Hill, SM, Sewitz, S et al.. Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters. Cell. 2016;167 (5):1369-1384.e19. doi: 10.1016/j.cell.2016.09.037. PubMed PMID:27863249 PubMed Central PMC5123897.
  10. Novakovic, B, Habibi, E, Wang, SY, Arts, RJ, Davar, R, Megchelenbrink, W et al.. β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance. Cell. 2016;167 (5):1354-1368.e14. doi: 10.1016/j.cell.2016.09.034. PubMed PMID:27863248 .
  11. Stunnenberg, HG, International Human Epigenome Consortium, Hirst, M. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. Cell. 2016;167 (5):1145-1149. doi: 10.1016/j.cell.2016.11.007. PubMed PMID:27863232 .
  12. Breeze, CE, Paul, DS, van Dongen, J, Butcher, LM, Ambrose, JC, Barrett, JE et al.. eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data. Cell Rep. 2016;17 (8):2137-2150. doi: 10.1016/j.celrep.2016.10.059. PubMed PMID:27851974 PubMed Central PMC5120369.
  13. Schuyler, RP, Merkel, A, Raineri, E, Altucci, L, Vellenga, E, Martens, JH et al.. Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems. Cell Rep. 2016;17 (8):2101-2111. doi: 10.1016/j.celrep.2016.10.054. PubMed PMID:27851971 .
  14. Mandoli, A, Singh, AA, Prange, KH, Tijchon, E, Oerlemans, M, Dirks, R et al.. The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs. Cell Rep. 2016;17 (8):2087-2100. doi: 10.1016/j.celrep.2016.08.082. PubMed PMID:27851970 .
  15. De Simone, M, Arrigoni, A, Rossetti, G, Gruarin, P, Ranzani, V, Politano, C et al.. Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells. Immunity. 2016;45 (5):1135-1147. doi: 10.1016/j.immuni.2016.10.021. PubMed PMID:27851914 PubMed Central PMC5119953.
  16. Queirós, AC, Beekman, R, Vilarrasa-Blasi, R, Duran-Ferrer, M, Clot, G, Merkel, A et al.. Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage. Cancer Cell. 2016;30 (5):806-821. doi: 10.1016/j.ccell.2016.09.014. PubMed PMID:27846393 .
  17. Tesselaar, MH, Crezee, T, Swarts, HG, Gerrits, D, Boerman, OC, Koenderink, JB et al.. Digitalis-like Compounds Facilitate Non-Medullary Thyroid Cancer Redifferentiation through Intracellular Ca2+, FOS, and Autophagy-Dependent Pathways. Mol. Cancer Ther. 2017;16 (1):169-181. doi: 10.1158/1535-7163.MCT-16-0460. PubMed PMID:27837029 .
  18. Tahmasebi, S, Jafarnejad, SM, Tam, IS, Gonatopoulos-Pournatzis, T, Matta-Camacho, E, Tsukumo, Y et al.. Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2. Proc. Natl. Acad. Sci. U.S.A. 2016;113 (44):12360-12367. doi: 10.1073/pnas.1615540113. PubMed PMID:27791185 PubMed Central PMC5098618.
  19. Spruijt, CG, Luijsterburg, MS, Menafra, R, Lindeboom, RG, Jansen, PW, Edupuganti, RR et al.. ZMYND8 Co-localizes with NuRD on Target Genes and Regulates Poly(ADP-Ribose)-Dependent Recruitment of GATAD2A/NuRD to Sites of DNA Damage. Cell Rep. 2016;17 (3):783-798. doi: 10.1016/j.celrep.2016.09.037. PubMed PMID:27732854 .
  20. Smid, M, Rodríguez-González, FG, Sieuwerts, AM, Salgado, R, Prager-Van der Smissen, WJ, Vlugt-Daane, MV et al.. Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration. Nat Commun. 2016;7 :12910. doi: 10.1038/ncomms12910. PubMed PMID:27666519 PubMed Central PMC5052682.
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