Publications

  1. Ung, DC, Iacono, G, Méziane, H, Blanchard, E, Papon, MA, Selten, M et al.. Ptchd1 deficiency induces excitatory synaptic and cognitive dysfunctions in mouse. Mol. Psychiatry. 2017; :. doi: 10.1038/mp.2017.39. PubMed PMID:28416808 .
  2. Davies, H, Glodzik, D, Morganella, S, Yates, LR, Staaf, J, Zou, X et al.. HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures. Nat. Med. 2017;23 (4):517-525. doi: 10.1038/nm.4292. PubMed PMID:28288110 .
  3. Cheung, WA, Shao, X, Morin, A, Siroux, V, Kwan, T, Ge, B et al.. Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome. Genome Biol. 2017;18 (1):50. doi: 10.1186/s13059-017-1173-7. PubMed PMID:28283040 PubMed Central PMC5346261.
  4. Dell'Aversana, C, Giorgio, C, D'Amato, L, Lania, G, Matarese, F, Saeed, S et al.. miR-194-5p/BCLAF1 deregulation in AML tumorigenesis. Leukemia. 2017; :. doi: 10.1038/leu.2017.64. PubMed PMID:28216661 .
  5. Liu, NQ, Ter Huurne, M, Nguyen, LN, Peng, T, Wang, SY, Studd, JB et al.. The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression. Nat Commun. 2017;8 :14418. doi: 10.1038/ncomms14418. PubMed PMID:28195176 PubMed Central PMC5316867.
  6. Kalkan, T, Olova, N, Roode, M, Mulas, C, Lee, HJ, Nett, I et al.. Tracking the embryonic stem cell transition from ground state pluripotency. Development. 2017;144 (7):1221-1234. doi: 10.1242/dev.142711. PubMed PMID:28174249 .
  7. Ecker, S, Chen, L, Pancaldi, V, Bagger, FO, Fernández, JM, Carrillo de Santa Pau, E et al.. Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. Genome Biol. 2017;18 (1):18. doi: 10.1186/s13059-017-1156-8. PubMed PMID:28126036 PubMed Central PMC5270224.
  8. Prange, KH, Mandoli, A, Kuznetsova, T, Wang, SY, Sotoca, AM, Marneth, AE et al.. MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia. Oncogene. 2017; :. doi: 10.1038/onc.2016.488. PubMed PMID:28114278 .
  9. Glodzik, D, Morganella, S, Davies, H, Simpson, PT, Li, Y, Zou, X et al.. A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nat. Genet. 2017;49 (3):341-348. doi: 10.1038/ng.3771. PubMed PMID:28112740 .
  10. Tomaz, RA, Harman, JL, Karimlou, D, Weavers, L, Fritsch, L, Bou-Kheir, T et al.. Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation. Development. 2017;144 (4):567-579. doi: 10.1242/dev.142489. PubMed PMID:28087629 PubMed Central PMC5312034.
  11. D'Aniello, C, Habibi, E, Cermola, F, Paris, D, Russo, F, Fiorenzano, A et al.. Vitamin C and l-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum. Stem Cell Reports. 2017;8 (1):1-10. doi: 10.1016/j.stemcr.2016.11.011. PubMed PMID:28017658 PubMed Central PMC5233408.
  12. Stunnenberg, HG, International Human Epigenome Consortium, Hirst, M. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. Cell. 2016;167 (7):1897. doi: 10.1016/j.cell.2016.12.002. PubMed PMID:27984737 .
  13. Dirks, RA, Stunnenberg, HG, Marks, H. Genome-wide epigenomic profiling for biomarker discovery. Clin Epigenetics. 2016;8 :122. doi: 10.1186/s13148-016-0284-4. PubMed PMID:27895806 PubMed Central PMC5117701.
  14. Farlik, M, Halbritter, F, Müller, F, Choudry, FA, Ebert, P, Klughammer, J et al.. DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation. Cell Stem Cell. 2016;19 (6):808-822. doi: 10.1016/j.stem.2016.10.019. PubMed PMID:27867036 PubMed Central PMC5145815.
  15. Arts, RJ, Novakovic, B, Ter Horst, R, Carvalho, A, Bekkering, S, Lachmandas, E et al.. Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metab. 2016;24 (6):807-819. doi: 10.1016/j.cmet.2016.10.008. PubMed PMID:27866838 .
  16. Astle, WJ, Elding, H, Jiang, T, Allen, D, Ruklisa, D, Mann, AL et al.. The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Cell. 2016;167 (5):1415-1429.e19. doi: 10.1016/j.cell.2016.10.042. PubMed PMID:27863252 PubMed Central PMC5300907.
  17. Chen, L, Ge, B, Casale, FP, Vasquez, L, Kwan, T, Garrido-Martín, D et al.. Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. Cell. 2016;167 (5):1398-1414.e24. doi: 10.1016/j.cell.2016.10.026. PubMed PMID:27863251 PubMed Central PMC5119954.
  18. Javierre, BM, Burren, OS, Wilder, SP, Kreuzhuber, R, Hill, SM, Sewitz, S et al.. Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters. Cell. 2016;167 (5):1369-1384.e19. doi: 10.1016/j.cell.2016.09.037. PubMed PMID:27863249 PubMed Central PMC5123897.
  19. Novakovic, B, Habibi, E, Wang, SY, Arts, RJ, Davar, R, Megchelenbrink, W et al.. β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance. Cell. 2016;167 (5):1354-1368.e14. doi: 10.1016/j.cell.2016.09.034. PubMed PMID:27863248 .
  20. Stunnenberg, HG, International Human Epigenome Consortium, Hirst, M. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. Cell. 2016;167 (5):1145-1149. doi: 10.1016/j.cell.2016.11.007. PubMed PMID:27863232 .
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