Publications

  1. Dell'Aversana, C, Giorgio, C, D'Amato, L, Lania, G, Matarese, F, Saeed, S et al.. miR-194-5p/BCLAF1 deregulation in AML tumorigenesis. Leukemia. 2017; :. doi: 10.1038/leu.2017.64. PubMed PMID:28216661 .
  2. Liu, NQ, Ter Huurne, M, Nguyen, LN, Peng, T, Wang, SY, Studd, JB et al.. The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression. Nat Commun. 2017;8 :14418. doi: 10.1038/ncomms14418. PubMed PMID:28195176 .
  3. Kalkan, T, Olova, N, Roode, M, Mulas, C, Lee, HJ, Nett, I et al.. Tracking the embryonic stem cell transition from ground state pluripotency. Development. 2017; :. doi: 10.1242/dev.142711. PubMed PMID:28174249 .
  4. Ecker, S, Chen, L, Pancaldi, V, Bagger, FO, Fernández, JM, Carrillo de Santa Pau, E et al.. Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types. Genome Biol. 2017;18 (1):18. doi: 10.1186/s13059-017-1156-8. PubMed PMID:28126036 PubMed Central PMC5270224.
  5. Prange, KH, Mandoli, A, Kuznetsova, T, Wang, SY, Sotoca, AM, Marneth, AE et al.. MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia. Oncogene. 2017; :. doi: 10.1038/onc.2016.488. PubMed PMID:28114278 .
  6. Glodzik, D, Morganella, S, Davies, H, Simpson, PT, Li, Y, Zou, X et al.. A somatic-mutational process recurrently duplicates germline susceptibility loci and tissue-specific super-enhancers in breast cancers. Nat. Genet. 2017;49 (3):341-348. doi: 10.1038/ng.3771. PubMed PMID:28112740 .
  7. Tomaz, RA, Harman, JL, Karimlou, D, Weavers, L, Fritsch, L, Bou-Kheir, T et al.. Jmjd2c facilitates the assembly of essential enhancer-protein complexes at the onset of embryonic stem cell differentiation. Development. 2017;144 (4):567-579. doi: 10.1242/dev.142489. PubMed PMID:28087629 .
  8. D'Aniello, C, Habibi, E, Cermola, F, Paris, D, Russo, F, Fiorenzano, A et al.. Vitamin C and l-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum. Stem Cell Reports. 2017;8 (1):1-10. doi: 10.1016/j.stemcr.2016.11.011. PubMed PMID:28017658 PubMed Central PMC5233408.
  9. Stunnenberg, HG, International Human Epigenome Consortium, Hirst, M. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. Cell. 2016;167 (7):1897. doi: 10.1016/j.cell.2016.12.002. PubMed PMID:27984737 .
  10. Dirks, RA, Stunnenberg, HG, Marks, H. Genome-wide epigenomic profiling for biomarker discovery. Clin Epigenetics. 2016;8 :122. doi: 10.1186/s13148-016-0284-4. PubMed PMID:27895806 PubMed Central PMC5117701.
  11. Farlik, M, Halbritter, F, Müller, F, Choudry, FA, Ebert, P, Klughammer, J et al.. DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation. Cell Stem Cell. 2016;19 (6):808-822. doi: 10.1016/j.stem.2016.10.019. PubMed PMID:27867036 PubMed Central PMC5145815.
  12. Arts, RJ, Novakovic, B, Ter Horst, R, Carvalho, A, Bekkering, S, Lachmandas, E et al.. Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metab. 2016;24 (6):807-819. doi: 10.1016/j.cmet.2016.10.008. PubMed PMID:27866838 .
  13. Astle, WJ, Elding, H, Jiang, T, Allen, D, Ruklisa, D, Mann, AL et al.. The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Cell. 2016;167 (5):1415-1429.e19. doi: 10.1016/j.cell.2016.10.042. PubMed PMID:27863252 PubMed Central PMC5300907.
  14. Chen, L, Ge, B, Casale, FP, Vasquez, L, Kwan, T, Garrido-Martín, D et al.. Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. Cell. 2016;167 (5):1398-1414.e24. doi: 10.1016/j.cell.2016.10.026. PubMed PMID:27863251 PubMed Central PMC5119954.
  15. Javierre, BM, Burren, OS, Wilder, SP, Kreuzhuber, R, Hill, SM, Sewitz, S et al.. Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters. Cell. 2016;167 (5):1369-1384.e19. doi: 10.1016/j.cell.2016.09.037. PubMed PMID:27863249 PubMed Central PMC5123897.
  16. Novakovic, B, Habibi, E, Wang, SY, Arts, RJ, Davar, R, Megchelenbrink, W et al.. β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance. Cell. 2016;167 (5):1354-1368.e14. doi: 10.1016/j.cell.2016.09.034. PubMed PMID:27863248 .
  17. Stunnenberg, HG, International Human Epigenome Consortium, Hirst, M. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery. Cell. 2016;167 (5):1145-1149. doi: 10.1016/j.cell.2016.11.007. PubMed PMID:27863232 .
  18. Breeze, CE, Paul, DS, van Dongen, J, Butcher, LM, Ambrose, JC, Barrett, JE et al.. eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data. Cell Rep. 2016;17 (8):2137-2150. doi: 10.1016/j.celrep.2016.10.059. PubMed PMID:27851974 PubMed Central PMC5120369.
  19. Schuyler, RP, Merkel, A, Raineri, E, Altucci, L, Vellenga, E, Martens, JH et al.. Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems. Cell Rep. 2016;17 (8):2101-2111. doi: 10.1016/j.celrep.2016.10.054. PubMed PMID:27851971 .
  20. Mandoli, A, Singh, AA, Prange, KH, Tijchon, E, Oerlemans, M, Dirks, R et al.. The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs. Cell Rep. 2016;17 (8):2087-2100. doi: 10.1016/j.celrep.2016.08.082. PubMed PMID:27851970 .
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