Publications

  1. Qu, J, Tanis, SEJ, Smits, JPH, Kouwenhoven, EN, Oti, M, van den Bogaard, EH et al.. Mutant p63 Affects Epidermal Cell Identity through Rewiring the Enhancer Landscape. Cell Rep. 2018;25 (12):3490-3503.e4. doi: 10.1016/j.celrep.2018.11.039. PubMed PMID:30566872 .
  2. Teo, K, Gómez-Cuadrado, L, Tenhagen, M, Byron, A, Rätze, M, van Amersfoort, M et al.. E-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancer. Sci Rep. 2018;8 (1):15454. doi: 10.1038/s41598-018-33525-5. PubMed PMID:30337563 PubMed Central PMC6193986.
  3. Grassi, L, Pourfarzad, F, Ullrich, S, Merkel, A, Were, F, Carrillo-de-Santa-Pau, E et al.. Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils. Cell Rep. 2018;24 (10):2784-2794. doi: 10.1016/j.celrep.2018.08.018. PubMed PMID:30184510 PubMed Central PMC6326331.
  4. Hornig, NC, Rodens, P, Dörr, H, Hubner, NC, Kulle, AE, Schweikert, HU et al.. Epigenetic Repression of Androgen Receptor Transcription in Mutation-Negative Androgen Insensitivity Syndrome (AIS Type II). J. Clin. Endocrinol. Metab. 2018;103 (12):4617-4627. doi: 10.1210/jc.2018-00052. PubMed PMID:30124873 .
  5. Richter, L, Landsverk, OJB, Atlasy, N, Bujko, A, Yaqub, S, Horneland, R et al.. Transcriptional profiling reveals monocyte-related macrophages phenotypically resembling DC in human intestine. Mucosal Immunol. 2018;11 (5):1512-1523. doi: 10.1038/s41385-018-0060-1. PubMed PMID:30038215 .
  6. Bernardo, AS, Jouneau, A, Marks, H, Kensche, P, Kobolak, J, Freude, K et al.. Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state. Biol Open. 2018;7 (8):. doi: 10.1242/bio.033282. PubMed PMID:30026265 PubMed Central PMC6124576.
  7. Søndergaard, JN, van Heeringen, SJ, Looman, MWG, Tang, C, Triantis, V, Louche, P et al.. Dendritic Cells Actively Limit Interleukin-10 Production Under Inflammatory Conditions via DC-SCRIPT and Dual-Specificity Phosphatase 4. Front Immunol. 2018;9 :1420. doi: 10.3389/fimmu.2018.01420. PubMed PMID:29988341 PubMed Central PMC6023963.
  8. van Buggenum, JAG, Gerlach, JP, Tanis, SEJ, Hogeweg, M, Jansen, PWTC, Middelwijk, J et al.. Immuno-detection by sequencing enables large-scale high-dimensional phenotyping in cells. Nat Commun. 2018;9 (1):2384. doi: 10.1038/s41467-018-04761-0. PubMed PMID:29921844 PubMed Central PMC6008431.
  9. Singh, AA, Petraglia, F, Nebbioso, A, Yi, G, Conte, M, Valente, S et al.. Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia. Oncotarget. 2018;9 (39):25647-25660. doi: 10.18632/oncotarget.25429. PubMed PMID:29876014 PubMed Central PMC5986653.
  10. Petraglia, F, Singh, AA, Carafa, V, Nebbioso, A, Conte, M, Scisciola, L et al.. Combined HAT/EZH2 modulation leads to cancer-selective cell death. Oncotarget. 2018;9 (39):25630-25646. doi: 10.18632/oncotarget.25428. PubMed PMID:29876013 PubMed Central PMC5986654.
  11. Beekman, R, Chapaprieta, V, Russiñol, N, Vilarrasa-Blasi, R, Verdaguer-Dot, N, Martens, JHA et al.. The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia. Nat. Med. 2018;24 (6):868-880. doi: 10.1038/s41591-018-0028-4. PubMed PMID:29785028 .
  12. Atlasi, Y, Stunnenberg, HG. Brd4-independence in ground state pluripotency. Nat. Cell Biol. 2018;20 (5):513-515. doi: 10.1038/s41556-018-0099-y. PubMed PMID:29662177 .
  13. Dubos, A, Meziane, H, Iacono, G, Curie, A, Riet, F, Martin, C et al.. A new mouse model of ARX dup24 recapitulates the patients' behavioral and fine motor alterations. Hum. Mol. Genet. 2018;27 (12):2138-2153. doi: 10.1093/hmg/ddy122. PubMed PMID:29659809 PubMed Central PMC5985730.
  14. Iacono, G, Dubos, A, Méziane, H, Benevento, M, Habibi, E, Mandoli, A et al.. Increased H3K9 methylation and impaired expression of Protocadherins are associated with the cognitive dysfunctions of the Kleefstra syndrome. Nucleic Acids Res. 2018;46 (10):4950-4965. doi: 10.1093/nar/gky196. PubMed PMID:29554304 PubMed Central PMC6007260.
  15. Carafa, V, Nebbioso, A, Cuomo, F, Rotili, D, Cobellis, G, Bontempo, P et al.. RIP1-HAT1-SIRT Complex Identification and Targeting in Treatment and Prevention of Cancer. Clin. Cancer Res. 2018;24 (12):2886-2900. doi: 10.1158/1078-0432.CCR-17-3081. PubMed PMID:29535128 .
  16. Bertero, A, Brown, S, Madrigal, P, Osnato, A, Ortmann, D, Yiangou, L et al.. The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency. Nature. 2018;555 (7695):256-259. doi: 10.1038/nature25784. PubMed PMID:29489750 PubMed Central PMC5951268.
  17. Arts, RJW, Moorlag, SJCFM, Novakovic, B, Li, Y, Wang, SY, Oosting, M et al.. BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity. Cell Host Microbe. 2018;23 (1):89-100.e5. doi: 10.1016/j.chom.2017.12.010. PubMed PMID:29324233 .
  18. Iacono, G, Benevento, M, Dubos, A, Herault, Y, van Bokhoven, H, Nadif Kasri, N et al.. Integrated transcriptional analysis unveils the dynamics of cellular differentiation in the developing mouse hippocampus. Sci Rep. 2017;7 (1):18073. doi: 10.1038/s41598-017-18287-w. PubMed PMID:29273784 PubMed Central PMC5741714.
  19. Bujko, A, Atlasy, N, Landsverk, OJB, Richter, L, Yaqub, S, Horneland, R et al.. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J. Exp. Med. 2018;215 (2):441-458. doi: 10.1084/jem.20170057. PubMed PMID:29273642 PubMed Central PMC5789404.
  20. Dell'Aversana, C, Giorgio, C, D'Amato, L, Lania, G, Matarese, F, Saeed, S et al.. miR-194-5p/BCLAF1 deregulation in AML tumorigenesis. Leukemia. 2018;32 (2):573. doi: 10.1038/leu.2017.310. PubMed PMID:29271969 .
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