In the September issue of Science, 3 papers from the BLUEPRINT consortium are published. BLUEPRINT is a large-scale research project receiving close to 30 million euro funding from the EU. Henk Stunnenberg is coordinating this consortium consisting of 39 leading European universities, research institutes and industry entrepreneurs. All 3 papers describe research which had an important input from the department of Molecular Biology.
1. mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity
2. Transcriptional diversity during lineage commitment of human blood progenitors
3. Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity